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An epidemiologic study of very low and very very low birth weight infants
Insights
Preventing prematurity is possible, as suggested by French and US experiences. Comprehensive child health programs are crucial for reducing infant mortality, including for normal birth weight infants.
Area of Science:
- Neonatology
- Public Health
- Perinatal Medicine
Background:
- Very-low-birth-weight (VLBW) infants are 1% of births but cause 60% of neonatal mortality and 40% of infant mortality.
- Despite advances, the prematurity rate decline is slow, necessitating strategies to prevent preterm birth and its consequences.
Purpose of the Study:
- To explore the potential for preventing prematurity and reducing its impact.
- To highlight the need for comprehensive preventive child health programs.
Main Methods:
- Review of recent experiences in France and the United States regarding prematurity prevention.
- Analysis of infant mortality data, including VLBW and normal birth weight infants.
Main Results:
- Positive outcomes in France and the US suggest prematurity prevention is achievable.
- A significant portion of first-year deaths occurs in normal birth weight infants, underscoring the need for broader interventions.
Conclusions:
- Preventive strategies, inspired by international experiences, can reduce prematurity.
- Holistic child health programs, from pre-conception through infancy, are essential for decreasing overall infant mortality.
Abstract:
VVLBW infants constitute only 1 per cent of the total births, but account for 60 per cent of the NMR and 40 per cent of the IMR. While improved technology and refinements in care continue to improve survival for VVLBW infants, questions regarding the lower limits of viability must be considered. The medical community can rightly take credit for improvement in outcome of infants with weight and gestations so small that, just a decade ago, they were considered nonviable; however, an excruciatingly slow pace of decline in the prematurity rate is an agonizing fact. Can anything be done to prevent prematurity and avoid its devastating consequences on the family and society? The recent French experience suggests the answer could be "yes." A similar experience also has been reported in the United States. Although VLBW NMR is a major fraction of total IMR, nearly one quarter of first-year deaths occur in infants who are over 2500 gm at birth. That the postneonatal death of normal birth weight infants is only next in magnitude to the neonatal death of VLBW infants further points to the need for developing preventive child health programs encompassing periods before and during the pregnancy, through the immediate peripartum period, and well into infancy and childhood. Neither a woman's pregnancy experience nor the concerns of the health community end with her taking a baby home.