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Updated: Jul 30, 2025

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
Published on: October 17, 2016
Swept-source multimode fiber imaging
Benjamin Lochocki1, Aleksandra Ivanina2, Akje Bandhoe2
1Nanoscale Imaging and Metrology, Advanced Research Center for Nanolithography (ARCNL), Science Park 106, 1098 XG, Amsterdam, The Netherlands. lochocki@arcnl.nl.
Abstract:
High-resolution compressive imaging via a flexible multimode fiber is demonstrated using a swept-laser source and wavelength dependent speckle illumination. An in-house built swept-source allowing for independent control of bandwidth and scanning range is used to explore and demonstrate a mechanically scan-free approach for high-resolution imaging through an ultrathin and flexible fiber probe. The computational image reconstruction is shown by utilizing a narrow sweeping bandwidth of [Formula: see text] nm while acquisition time is decreased by 95% compared to conventional raster scanning endoscopy. Demonstrated narrow-band illumination in the visible spectrum is vital for the detection of fluorescence biomarkers in neuroimaging applications. The proposed approach yields device simplicity and flexibility for minimally invasive endoscopy.
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