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Surgical Management of Autosomal Dominant Polycystic Kidney Disease: Principles and Current Practice

Badri Man Shrestha1

  • 1Sheffield Kidney Institute, Sheffield Teaching Hospitals NHS Trust, Sheffield, United Kingdom.

JNMA; Journal of the Nepal Medical Association
|May 19, 2023
PubMed

Insights

Autosomal dominant polycystic kidney disease (ADPKD) is a leading cause of kidney failure. This review covers surgical management principles for ADPKD complications, including nephrectomy and transplantation.

Area of Science:

  • Nephrology
  • Surgical Management
  • Renal Failure

Background:

  • Autosomal dominant polycystic kidney disease (ADPKD) is the third most common cause of end-stage renal disease.
  • Currently, no definitive treatments exist to halt cyst development and growth in ADPKD.
  • Medical treatments aim to slow cyst progression and preserve kidney function.

Conclusions:

  • Surgical management is a critical component in addressing complications of ADPKD.
  • Nephrectomy and transplantation are essential for improving outcomes in advanced ADPKD.
  • Further research into targeted therapies alongside surgical options is warranted.

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