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Updated: Jul 29, 2025

Resolving Affinity Purified Protein Complexes by Blue Native PAGE and Protein Correlation Profiling
Published on: April 1, 2017
Activity-based protein profiling - finding general solutions to specific problems
1The Department of Chemistry, The Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92037.
This perspective discusses the development and application of activity-based protein profiling (ABPP) technology over 25 years. It highlights the contributions of colleagues to a special issue on innovative science.
Area of Science:
- Biochemistry
- Chemical Biology
- Proteomics
Background:
- Activity-based protein profiling (ABPP) is a powerful chemical proteomics technology.
- The development and application of ABPP have been a major focus for the author's lab for over 25 years.
Purpose of the Study:
- To provide a retrospective and perspective on the development and application of ABPP technology.
- To acknowledge and thank colleagues who contributed to a special issue.
Main Methods:
- Retrospective analysis of the development of ABPP technology.
- Perspective on the application of ABPP in various scientific fields.
Main Results:
- The abstract does not contain specific results, as it is a perspective piece.
- It emphasizes the long-standing commitment to advancing ABPP technology.
Conclusions:
- The author reflects on the significant journey of ABPP technology.
- Appreciation is expressed for the collaborative efforts within the scientific community.
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