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Updated: Jul 29, 2025

Author Spotlight: Deciphering the Long-Term Effects of Low-Level Blast Exposures in Mice
Published on: May 24, 2024
High risk and low prevalence diseases: Blast injuries
Josh Bukowski1, Craig D Nowadly1, Steven G Schauer2
1Department of Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, TX, USA.
Introduction:
Blast injury is a unique condition that carries a high rate of morbidity and mortality, often with mixed penetrating and blunt injuries.
Objective:
This review highlights the pearls and pitfalls of blast injuries, including presentation, diagnosis, and management in the emergency department (ED) based on current evidence.
Discussion:
Explosions may impact multiple organ systems through several mechanisms. Patients with suspected blast injury and multisystem trauma require a systematic evaluation and resuscitation, as well as investigation for injuries specific to blast injuries. Blast injuries most commonly affect air-filled organs but can also result in severe cardiac and brain injury. Understanding blast injury patterns and presentations is essential to avoid misdiagnosis and balance treatment of competing interests of patients with polytrauma. Management of blast victims can also be further complicated by burns, crush injury, resource limitation, and wound infection. Given the significant morbidity and mortality associated with blast injury, identification of various injury patterns and appropriate management are essential.
Conclusions:
An understanding of blast injuries can assist emergency clinicians in diagnosing and managing this potentially deadly disease.
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