Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Association of systemic inflammation with major adverse cardiovascular events in patients with acute myocardial infarction.

American journal of preventive cardiology·2026

Same author

First-in-Human Transcatheter Aortic Root Tricuspidization of Stenotic Bicuspid Valves: A Strategy to Optimize TAVR.

JACC. Cardiovascular interventions·2026

Same author

Intratumoral TLR4 agonist therapy elicits antigen-specific T cell clonal expansion in metastatic leiomyosarcoma: a case series.

Frontiers in oncology·2026

Same author

Safety and Effectiveness of Saphenous Vein Graft Use for Retrograde Chronic Total Occlusion Percutaneous Coronary Intervention.

The American journal of cardiology·2026

Same author

Proton Beam Therapy for Large Localized Hepatocellular Carcinomas in Western Patients.

International journal of radiation oncology, biology, physics·2026

Same author

The impact of walking on creative thinking: A systematic review and meta-analysis.

PloS one·2026

Same journal

Addressing barriers to care: A proposed model to predict prolonged treatment time among patients with locally advanced cervical cancer.

Brachytherapy·2026

Same journal

EM-tracked MR-US live fusion and needle location in gynecologic brachytherapy.

Brachytherapy·2026

Same journal

Contour and dosimetric evaluation of an in-room mobile CBCT scanner for cylinder based brachytherapy.

Brachytherapy·2026

Same journal

Brachytherapy for rectal cancer: An overview of clinical competency development in contemporary practice.

Brachytherapy·2026

Same journal

Deep learning-based automatic segmentation of rectal tumors in endoscopic images.

Brachytherapy·2026

Same journal

Online educational program for CT-based image-guided adaptive brachytherapy in cervical cancer: The BrachyAcademy experience.

Brachytherapy·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 29, 2025

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

Image-guided intravascular brachytherapy dose escalation.

Luke Lussier¹, Kent Wallner², Kathleen E Kearney³

¹Department of Physics, St. Mary's University, San Antonio, TX.

|May 21, 2023

Summary

This summary is machine-generated.

Coronary stents significantly reduce intravascular brachytherapy (IVBT) radiation dose, with multiple layers and expansion further decreasing effectiveness. Individualized dose adjustments are crucial for optimizing IVBT delivery.

Keywords:

Brachytherapy Cardiac Coronary Heart Oncology Radiation Restenosis

More Related Videos

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Published on: December 2, 2013

Related Experiment Videos

Last Updated: Jul 29, 2025

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Dual-phase Cone-beam Computed Tomography to See, Reach, and Treat Hepatocellular Carcinoma during Drug-eluting Beads Transarterial Chemo-embolization

Published on: December 2, 2013

Area of Science:

Medical Physics
Radiation Oncology
Cardiovascular Interventions

Background:

Coronary stents are used in intravascular brachytherapy (IVBT) to reduce radiation dose.
The impact of multiple stent layers and stent expansion on IVBT dose reduction is not well understood.

Purpose of the Study:

To investigate the effect of multiple stent layers and varying stent densities on radiation dose delivered during IVBT.
To explore the potential for individualized dose adjustments in IVBT based on stent characteristics.

Main Methods:

Utilized EGSnrc simulations to compute vessel wall doses in various IVBT scenarios.
Modeled stent effects with densities of 25%, 50%, and 75% across 1, 2, and 3 layers.
Calculated doses at radial distances from 1.75 to 5.00 mm, normalized to 2 mm.

Main Results:

Increased stent density led to greater dose fall-off.
A single stent layer reduced the dose at 2 mm to 92%, 83%, and 73% for 25%, 50%, and 75% density, respectively.
Three layers at 75% density reduced the dose at 2 mm to 38%.

Conclusions:

A schema for image-guided IVBT dose adjustment was proposed.
Acknowledged that optimizing IVBT requires addressing numerous factors beyond stent characteristics.
Emphasized the need for further research to refine IVBT treatment planning.