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Researching COVID to enhance recovery (RECOVER) pediatric study protocol: Rationale, objectives and design
Rachel Gross1, Tanayott Thaweethai2, Erika B Rosenzweig3
1Department of Pediatrics, New York University Grossman School of Medicine, New York, NY, USA.
The RECOVER-Pediatrics study protocol outlines a large-scale investigation into Long COVID (post-acute sequelae of SARS-CoV-2) in youth. This research aims to define PASC, its mechanisms, and potential treatments in children and young adults.
Area of Science:
- Pediatric Health
- Infectious Diseases
- Epidemiology
Background:
- The long-term effects and mechanisms of post-acute sequelae of SARS-CoV-2 (PASC), or Long COVID, in children and young adults are not well understood.
- There is an urgent need to define PASC in pediatric populations to identify mechanisms and potential therapeutic targets.
Conclusions:
- The RECOVER-Pediatrics protocol provides a framework for a comprehensive investigation into the impact of PASC on children and young adults.
- Findings from this study are expected to significantly advance the understanding of pediatric PASC, informing clinical care and therapeutic strategies.
- The adaptive and collaborative nature of the protocol ensures its relevance and responsiveness to emerging scientific knowledge.
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