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Related Experiment Videos

Nickel sensitivity in Singapore.

T T Moorthy, G H Tan

    International Journal of Dermatology
    |June 1, 1986
    PubMed
    Summary

    Nickel allergy is a common cause of allergic contact dermatitis in Singapore, particularly affecting women. Patch tests reveal prevalence and common sources like jewelry and clothing fasteners.

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    Area of Science:

    • Dermatology
    • Allergology
    • Epidemiology

    Background:

    • Nickel is a frequent trigger for allergic contact dermatitis (ACD).
    • Understanding the prevalence and characteristics of nickel allergy is crucial for public health in Singapore.

    Purpose of the Study:

    • To determine the prevalence of nickel allergy in Singapore.
    • To identify common sources of nickel exposure.
    • To analyze demographic and clinical associations, including hand eczema, atopy, and cobalt sensitivity.

    Main Methods:

    • Analysis of patch test results from patients in Singapore.
    • Data collection on patient demographics, clinical history, and exposure sources.
    • Statistical evaluation of positive nickel reactions and associated conditions.

    Main Results:

    • Nickel allergy showed positive patch test reactions in 7-14% of patients.
    • Women were more frequently affected with an earlier age of onset (21 years) compared to men (32 years).
    • Common sources included wristwatches, earrings, buttons, and necklaces; 25% had hand eczema, 36% had atopy, and 37% reacted to cobalt.

    Conclusions:

    • Nickel allergy is a significant dermatological issue in Singapore.
    • Awareness of common exposure sources and associated conditions like hand eczema and atopy is important for diagnosis and management.
    • Co-reactivity with cobalt warrants consideration in clinical practice.

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