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COVID-19 and Cerebrovascular Disease
Christina Catherine1, Julia Veitinger2, Sherry H-Y Chou2
1Department of Neurology, UPMC Altoona Regional Hospital, Altoona, Pennsylvania.
Seminars in Neurology
|May 22, 2023
Summary
COVID-19 can cause serious neurological issues, including ischemic stroke, which affects 1-6% of patients. This review covers COVID-19
Area of Science:
- Neurology
- Infectious Diseases
- Cardiovascular Medicine
Background:
- COVID-19 is linked to various neurological complications.
- Acute cerebrovascular disease is a severe complication.
- Ischemic stroke is the most frequent cerebrovascular event in COVID-19 patients.
Purpose of the Study:
- To review the incidence and mechanisms of COVID-19-associated cerebrovascular complications.
- To discuss risk factors, management, and prognosis.
- To explore pregnancy-related cerebrovascular events in COVID-19.
Main Methods:
- Literature review of COVID-19 and cerebrovascular events.
- Analysis of reported cases and proposed pathophysiological mechanisms.
- Discussion of clinical management and outcomes.
Main Results:
- Ischemic stroke occurs in 1-6% of COVID-19 patients.
- Mechanisms include vasculopathy, endotheliopathy, and platelet activation.
- Other complications include hemorrhagic stroke, PRES, RCVS, CVST, and SAH.
Conclusions:
- COVID-19 presents a significant risk for diverse cerebrovascular complications.
- Understanding mechanisms is crucial for effective management.
- Further research is needed, especially concerning pregnancy.
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