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Related Experiment Video

Updated: Jul 29, 2025

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats

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Published on: May 27, 2021

Functional tic-like presentations differ strikingly from Provisional Tic Disorder.

Amanda L Arbuckle¹, Emily C Bihun¹, Bradley L Schlaggar^2,3,4

¹Department of Psychiatry, Washington University in St. Louis, School of Medicine, St. Louis, Missouri, 63110, USA.

|May 24, 2023

Summary

This summary is machine-generated.

Functional Neurological Symptom Disorder (FND-tic) presents distinct symptoms compared to Tourette Syndrome (TS) and Provisional Tic Disorder (PTD). This study confirms FND-tic as a separate diagnosis with unique clinical features.

Keywords:

Conversion Disorder Diagnosis Differential Functional Neurological Symptom Disorder Provisional Tic Disorder Tic Disorders/classification Tourette Syndrome

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Published on: July 5, 2014

Area of Science:

Neurology
Psychiatry
Clinical Psychology

Background:

Recent surge in new-onset tics among adolescents and young adults.
These cases often exhibit rapid symptom onset, differing from typical Tourette Syndrome (TS).
Many are diagnosed with Functional Neurological Symptom Disorder (FND-tic), prompting debate on its distinction from TS and Provisional Tic Disorder (PTD).

Purpose of the Study:

To investigate if presenting symptoms of FND-tic differ from TS in patients with similar symptom duration.
To compare clinical features of FND-tic with those of PTD and TS.

Main Methods:

Comparative analysis of published FND-tic case reports and novel longitudinal data from 89 children with PTD.
Evaluation of symptom characteristics, course, severity, and comorbidity.
Focus on features previously identified as indicative of FND-tic.

Main Results:

Significant clinical differences observed between FND-tic and PTD patients.
Coprophenomena present in over half of FND-tic patients at onset, versus only one PTD patient.
Six clinical features demonstrated over 90% positive predictive value for FND-tic diagnosis.

Conclusions:

Findings provide strong evidence for the diagnostic validity of FND-tic.
FND-tic is presented as a distinct clinical entity separate from TS.
The study supports differentiating FND-tic from PTD based on specific symptom profiles.