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Determining a cut-off point for intervention analgesia in rabbits using the Bristol Rabbit Pain Scale
Livia Benato1, Joanna Murrell2, Nicola Rooney1
1Animal Welfare and Behaviour, School of Veterinary Sciences, University of Bristol, Langford, UK.
Background:
The objective of this study was to determine the threshold of the Bristol Rabbit Pain Scale (BRPS) indicating the need for intervention analgesia.
Methods:
Fourteen members of veterinary staff were recruited to rate rabbits (n = 71) in acute pain. Observers in group A (n = 7) were asked to score each rabbit using the BRPS, while observers in group B (n = 7) independently answered the question 'In your clinical capacity, do you think this animal requires analgesia?' with either 'Yes' or 'No'. The answers from the two groups were then compared.
Results:
Rabbits for which group B answered 'No' (n = 36) had a median BRPS score (range) of 4 (0-10), while those for which group B answered 'Yes' (n = 42) had a median BRPS score of 9 (1-18; Z = -7.48; p < 0.001). The area under the receiver operating characteristic curve was 0.85 (95% confidence interval: 0.77-0.93; p < 0.001), indicating excellent discrimination of the BRPS with a cut-off score of 5.5 (sensitivity 88.1% and specificity 69.4%). However, for practicality, a score of 5 was deemed a feasible cut-off.
Limitations:
The main limitations of this study are the small rabbit sample size and the subjective nature of pain scoring in animals.
Conclusions:
Analgesic intervention should be considered in rabbits with a pain score equal to or greater than 5 on the BRPS.
