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Dansyl-triazole-based fluorescent macrocycle for selective detection of nitro-antibiotic drugs and protein
Liya Thurakkal1, Rakhi Mol K M1, Mintu Porel1,2
1Department of Chemistry, Indian Institute of Technology Palakkad, Kerala 678557, India. mintu@iitpkd.ac.in.
Abstract:
A novel dansyl-triazole-based fluorescent macrocycle with high Stokes shift and positive solvatochromism was developed. This is an excellent fluorescence sensor for selective detection of nitro-containing antibiotics and other nitro-heteroaromatics. Detection was possible in real samples/paper strips in submicromolar concentration. The interaction of the macrocycle with multiple proteins exhibited its bioactivity.

