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Ceramic Omnidirectional Bioprinting in Cell-Laden Suspensions for the Generation of Bone Analogs
Published on: August 8, 2022
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CaSiO3-HAp Metal-Reinforced Biocomposite Ceramics for Bone Tissue Engineering
Evgeniy K Papynov1, Oleg O Shichalin1, Anton A Belov1
1Far Eastern Federal University, 10 Ajax Bay, Russky Island, 690922 Vladivostok, Russia.
Journal of Functional Biomaterials
|May 26, 2023
Summary
This study developed a novel CaSiO3-HAp bioceramic composite reinforced with Ti6Al4V alloy using spark plasma sintering for bone regeneration implants. The resulting material shows promising properties for advanced reconstructive bone surgery.
Area of Science:
- Biomaterials Science
- Materials Engineering
- Orthopedic Surgery
Background:
- Reconstructive bone surgery relies on advanced biocompatible implants for musculoskeletal restoration.
- Titanium alloy (Ti6Al4V) is a common choice for implants due to its low density and corrosion resistance.
- Calcium silicate (CaSiO3) and hydroxyapatite (HAp) are bioactive ceramics with potential for bone repair.
Purpose of the Study:
- To investigate the use of spark plasma sintering for creating CaSiO3-HAp bioceramic composites reinforced with Ti6Al4V alloy.
- To evaluate the properties of these novel ceramic-metal biocomposites for potential use in regenerative bone surgery.
Main Methods:
- Spark plasma sintering (SPS) was employed to consolidate CaSiO3-HAp powder with a Ti6Al4V matrix.
- X-ray fluorescence, SEM, EDS, and BET analysis were used to characterize the material's composition and structure.
- Vickers microhardness and critical stress intensity factor (KI) were assessed.
Main Results:
- Spark plasma sintering successfully produced an integral ceramic-metal biocomposite.
- The composite exhibited high Vickers microhardness values at the alloy, bioceramic, and interface regions.
- The study assessed the crack resistance (KI) of the developed material.
Conclusions:
- Spark plasma sintering is an effective method for producing CaSiO3-HAp/Ti6Al4V biocomposites.
- These novel materials show potential for developing high-tech implants for regenerative bone surgery.
- The research offers a promising avenue for advanced orthopedic implant development.

