Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cycloaddition Reactions: MO Requirements for Thermal Activation01:16

Cycloaddition Reactions: MO Requirements for Thermal Activation

3.6K
Thermal cycloadditions are reactions where the source of activation energy needed to initiate the reaction is provided in the form of heat. A typical example of a thermally-allowed cycloaddition is the Diels–Alder reaction, which is a [4 + 2] cycloaddition. In contrast, a [2 + 2] cycloaddition is thermally forbidden.
3.6K
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

7.9K
Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
7.9K
Stability of Substituted Cyclohexanes02:30

Stability of Substituted Cyclohexanes

12.7K
This lesson discusses the stability of substituted cyclohexanes with a focus on energies of various conformers and the effect of 1,3-diaxial interactions.
The two chair conformations of cyclohexanes undergo rapid interconversion at room temperature. Both forms have identical energies and stabilities, each comprising equal amounts of the equilibrium mixture. Replacing a hydrogen atom with a functional group makes the two conformations energetically non-equivalent.
For example, in...
12.7K
[3,3] Sigmatropic Rearrangement of 1,5-Dienes: Cope Rearrangement01:21

[3,3] Sigmatropic Rearrangement of 1,5-Dienes: Cope Rearrangement

2.8K
The Cope rearrangement is classified as a [3,3] sigmatropic shift in 1,5-dienes, leading to a more stable, isomeric 1,5-diene. The reaction involves a concerted movement of six electrons, four from two π bonds and two from a σ bond, via an energetically favorable chair-like transition state.
2.8K
[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction01:16

[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction

10.3K
The Diels–Alder reaction is an example of a thermal pericyclic reaction between a conjugated diene and an alkene or alkyne, commonly referred to as a dienophile. The reaction involves a concerted movement of six π electrons, four from the diene and two from the dienophile, forming an unsaturated six-membered ring. As a result, these reactions are classified as [4+2] cycloadditions.
10.3K
Cooperative Binding of Transcription Regulators02:13

Cooperative Binding of Transcription Regulators

6.5K
Transcriptional regulators bind to specific cis-regulatory sequences in the DNA to regulate gene transcription. These cis-regulatory sequences are very short, usually less than ten nucleotide pairs in length. The short length means that there is a high probability of the exact same sequence randomly occurring throughout the genome.  Since regulators can also bind to groups of similar sequences, this further increases the chances of random binding. Transcriptional regulators form...
6.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of intraoperative low-dose remimazolam maintenance on emergence agitation and emergence time in patients undergoing oral surgery: protocol for a randomized controlled trial.

Annals of medicine·2026
Same author

Boosting Photocatalytic Overall Water Splitting Activity of Phosphorene Through Five-Coordinate Passivation Enabled by Carbene Addition.

Angewandte Chemie (International ed. in English)·2026
Same author

Interfacial Engineering via Polishing and Dipolar Synergy Toward Efficient Inverted CsPbI<sub>3</sub> Perovskite Solar Cells.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

A Radial-Linear π-Conjugated Polymer by Integrating Poly(Para-phenylene Vinylene) and Cycloparaphenylene for Enhanced Optoelectronic and Electrochemical Performance.

Angewandte Chemie (International ed. in English)·2026
Same author

Identification of WRKY transcription factors (TFs) in the recretohalophyte Tamarix chinensis and functional analysis of TcWRKY13 under salt stress.

Plant cell reports·2026
Same author

The 1-hour plasma glucose as a specific marker for early-phase insulin secretory defects in young adults with obesity.

Diabetes research and clinical practice·2026

Related Experiment Video

Updated: Jul 29, 2025

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water
16:24

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water

Published on: August 2, 2012

18.7K

Regulating supramolecular interactions in dimeric macrocycles.

Pengwei Fang1,2, Muqing Chen1,2, Nan Yin2

  • 1School of Environment and Civil Engineering, Dongguan University of Technology Dongguan 523808 Guangdong Province China mqchen@ustc.edu.cn.

Chemical Science
|May 26, 2023
PubMed
Summary
This summary is machine-generated.

Researchers tuned supramolecular architectures using rigid macrocycles and guest molecules. Different configurations of these bismacrocycles enabled tunable host-guest complex formation, including unusual stoichiometries.

More Related Videos

Synthesis and Characterization of Supramolecular Colloids
09:26

Synthesis and Characterization of Supramolecular Colloids

Published on: April 22, 2016

9.9K
Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates
06:35

Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates

Published on: February 15, 2016

8.2K

Related Experiment Videos

Last Updated: Jul 29, 2025

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water
16:24

Controlling the Size, Shape and Stability of Supramolecular Polymers in Water

Published on: August 2, 2012

18.7K
Synthesis and Characterization of Supramolecular Colloids
09:26

Synthesis and Characterization of Supramolecular Colloids

Published on: April 22, 2016

9.9K
Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates
06:35

Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates

Published on: February 15, 2016

8.2K

Area of Science:

  • Supramolecular Chemistry
  • Organic Synthesis
  • Materials Science

Background:

  • Supramolecular behavior is influenced by microenvironments and weak interactions.
  • Controlling supramolecular architectures is crucial for designing functional materials.

Purpose of the Study:

  • To tune supramolecular architectures of rigid macrocycles.
  • To investigate the synergistic effects of geometric configuration, size, and guests on supramolecular behavior.
  • To develop a new strategy for constructing diverse supramolecular systems.

Main Methods:

  • Synthesis of two paraphenylene-based macrocycles anchored onto a triphenylene derivative, creating dimeric macrocycles with varied shapes and configurations.
  • Investigation of host-guest interactions using solid-state studies.
  • Characterization of supramolecular complexes formed with C60 and C70 fullerenes.

Main Results:

  • Dimeric macrocycles with distinct geometric configurations were successfully synthesized.
  • Tunable supramolecular interactions were observed based on macrocycle structure and guest molecules.
  • Specific host-guest complexes were identified: a 2:1 complex between macrocycle 1a and C60/C70, and an unusual 2:3 complex between macrocycle 1b and C60.

Conclusions:

  • Geometric configuration and size are key factors in tuning supramolecular architectures of rigid macrocycles.
  • The developed strategy provides a novel approach for synthesizing rigid bismacrocycles and constructing diverse supramolecular systems.
  • The observed tunable host-guest complexation expands possibilities in supramolecular chemistry and materials design.