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Author Spotlight: Eco-Friendly Extraction of Bioactive Compounds Using Polyol-Based Microwave-Assisted Techniques
Published on: August 23, 2024
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From Coffee Waste to Active Ingredient for Cosmetic Applications.
Giovanna Grigolon1, Kathrin Nowak1, Stéphane Poigny1
1Mibelle Group Biochemistry, Mibelle AG, 5033 Buchs, Switzerland.
International Journal of Molecular Sciences
|May 27, 2023
Summary
Coffee silverskin extract, a coffee roasting byproduct, shows promise for cosmetics. It protects skin from irritation, enhances hydration, and supports skin barrier function, offering an eco-friendly skincare solution.
Area of Science:
- Cosmetic Science
- Biotechnology
- Waste Valorization
Background:
- Coffee silverskin (CS) is a major byproduct of coffee roasting.
- CS is rich in bioactive compounds with potential cosmetic benefits.
- Reutilizing waste products aligns with sustainable practices.
Purpose of the Study:
- To investigate the cosmetic potential of coffee silverskin extract.
- To evaluate the efficacy of CS extract in skin protection and hydration.
- To develop an innovative, bio-inspired cosmetic active ingredient.
Main Methods:
- Supercritical CO2 extraction of coffee silverskin.
- Chemical profiling of the extract (e.g., cafestol, kahweol esters).
- In vitro gene expression studies on keratinocytes and in vivo skin irritation tests.
Main Results:
- The CS extract contains valuable bioactive molecules like cafestol and kahweol esters.
- In vitro studies showed upregulation of oxidative stress and skin barrier genes.
- In vivo tests demonstrated protection against SLS-induced irritation and improved skin hydration.
Conclusions:
- Coffee silverskin extract is a potent, bio-inspired cosmetic ingredient.
- It offers skin protection, enhances barrier function, and improves hydration.
- This sustainable ingredient provides environmental and skincare benefits.

