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Updated: Aug 12, 2026

Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia
Published on: May 9, 2013
Patient Selection Criteria and Procedural Standardization for Carotid Artery Stenting-A Single Center Experience
Paolo Calo1, Alexander Oberhuber2, Hartmut Görtz1
1Department of Vascular Surgery, Bonifatius Hospital Lingen, 49808 Lingen, Germany.
Insights
Carotid artery stenting (CAS) can achieve low complication rates in carefully selected patients. Standardizing CAS procedures and materials is crucial for patient safety and successful outcomes.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Neurology
Background:
- Carotid endarterectomy (CEA) is the gold standard for carotid artery stenosis.
- Carotid artery stenting (CAS) is an alternative, but randomized trials show higher stroke rates.
- Prior CAS trials had significant procedural heterogeneity.
Purpose of the Study:
- To evaluate the safety and efficacy of CAS in a highly selected patient cohort.
- To assess peri-interventional stroke and death rates following standardized CAS.
- To determine the impact of strict patient selection and procedural standardization on CAS outcomes.
Main Methods:
- Retrospective analysis of 202 patients undergoing CAS (2012-2020).
- Patients pre-selected based on strict anatomical and clinical criteria.
- Standardized CAS procedure and materials used, performed by experienced surgeons.
Main Results:
- 100% technical success rate for CAS.
- Low periprocedural complication rate of 1.5%.
- Included one major stroke (0.5%) and two minor strokes (1%).
Conclusions:
- Strict patient selection significantly reduces CAS complication rates.
- Standardization of CAS procedures and materials is essential for optimal safety.
- CAS is a safe and effective alternative to CEA when performed under stringent conditions.
Abstract:
The gold standard for the treatment of carotid artery stenosis is the carotid endarterectomy (CEA). According to current guidelines, carotid artery stenting (CAS) is an alternative. Randomized control trials (RCTs) show significantly higher rates of peri-interventional strokes after CAS compared to CEA. However, these trials were usually characterized by a great heterogeneity in the CAS procedure. In this retrospective analysis from 2012 to 2020, 202 symptomatic and asymptomatic patients were treated with CAS. Patients were carefully pre-selected according to anatomical and clinical criteria. In all cases, the same steps and material were used. All interventions were performed by five experienced vascular surgeons. Primary endpoints of this study were perioperative death and stroke. Asymptomatic carotid stenosis was present in 77% of the patients and symptomatic in 23%. The mean age was 66 years. The average degree of stenosis was 81%. The CAS technical success rate was 100%. Periprocedural complications occurred in 1.5% of cases, including one major stroke (0.5%) and two minor strokes (1%). The results of this study indicate that through a strict patient selection based on anatomical and clinical criteria, CAS can be performed with very low complication rates. Furthermore, standardization of the materials and the procedure itself is crucial.
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