Pulmonary Nodule Detection and Classification Using All-Optical Deep Diffractive Neural Network

A deep diffractive neural network (D2NN) is a fast optical computing structure that has been widely used in image classification, logical operations, and other fields. Computed tomography (CT) imaging is a reliable method for detecting and analyzing pulmonary nodules. In this paper, we propose using an all-optical D2NN for pulmonary nodule detection and classification based on CT imaging for lung cancer. The network was trained based on the LIDC-IDRI dataset, and the performance was evaluated on a test set. For pulmonary nodule detection, the existence of nodules scanned from CT images were estimated with two-class classification based on the network, achieving a recall rate of 91.08% from the test set. For pulmonary nodule classification, benign and malignant nodules were also classified with two-class classification with an accuracy of 76.77% and an area under the curve (AUC) value of 0.8292. Our numerical simulations show the possibility of using optical neural networks for fast medical image processing and aided diagnosis.