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Atrial Fibrillation Related Coronary Embolism: Diagnosis in the Focus
László Balogh1, Péter Óvári1, Christopher Uwaafo Ugbodaga1
1Department of Cardiology and Cardiac Surgery, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Insights
Atrial fibrillation (AF) is linked to coronary embolism (CE) in ST-elevation myocardial infarction (STEMI) patients. The Shibata criteria aid in diagnosing AF-related CE, with thrombus aspiration proving useful.
Area of Science:
- Cardiology
- Internal Medicine
- Vascular Medicine
Background:
- Atrial fibrillation (AF) is a common arrhythmia associated with myocardial infarction (MI).
- Coronary embolism (CE) accounts for 4-5% of MI cases, with AF being a significant contributor.
- The relationship between AF and MI, particularly AF-related CE, requires further investigation.
Purpose of the Study:
- To determine the prevalence of AF-related CE in ST-elevation myocardial infarction (STEMI) patients.
- To evaluate the diagnostic accuracy of the Shibata criteria for identifying AF-related CE.
- To assess the role of thrombus aspiration in diagnosing AF-related CE.
Main Methods:
- Retrospective analysis of 1181 STEMI patients over three years.
- Application of the Shibata criteria for classifying CE cases.
- PubMed search to identify and analyze previously reported AF-related CE cases.
Main Results:
- 13.2% of STEMI patients had AF (157 out of 1181).
- Shibata criteria identified 10 'definitive' and 31 'probable' CE cases, with 5 additional 'definitive' cases upon re-evaluation.
- CE was more frequent in patients with known AF (16.7%) versus new-onset AF (5.1%).
- Literature review found 40 applicable AF-related CE cases; 31 'definitive', 4 'probable'.
- Thrombus aspiration aided diagnosis in 47% of the study's cases and 40% of reported cases.
Conclusions:
- AF is a relevant factor in STEMI, with a notable prevalence of AF-related CE.
- The Shibata criteria are valuable for diagnosing AF-related CE.
- Thrombus aspiration can be a beneficial diagnostic tool in suspected AF-related CE.
Abstract:
Atrial fibrillation (AF) is the most common arrhythmia in myocardial infarction (MI). AF can be caused by ischemia, and MI can be caused by AF. Additionally, 4-5% of MI cases are related to coronary embolism (CE), and one-third of cases are attributed to AF. Our aim was to investigate the prevalence of AF-related CE cases among 3 consecutive years of STEMI cases. We also aimed to reveal the diagnostic accuracy of the Shibata criteria scoring system and the role of thrombus aspiration. Among 1181 STEMI patients, 157 had AF (13.2%). By using the Shibata's diagnostic criteria, 10 cases were classified as 'definitive' and 31 as 'probable' CE. After re-evaluation, a further five cases were classified as 'definitive'. Further analysis of the 15 CE cases revealed that CE was more prevalent in patients with previously known (n = 10) compared to those with new-onset (n = 5) AF (16.7% vs. 5.1%, p = 0.024). A PubMed search was performed, and 40 AF-related cases were found where the Shibata's criteria could be applied. Further, 31 cases could be classified as 'definitive', 4 as 'probable' and, in 5 cases, the embolic origin could be excluded. In 40% of reported cases and in 47% of our cases, thrombus aspiration helped in diagnosis.
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