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Updated: Jul 28, 2025

Gasless Endoscopic Thyroidectomy via the Trans-Axillary Approach
Published on: September 15, 2023
Large goiters and postoperative complications: does it really matter?
Joaquín Gómez-Ramírez1, Paula Cubillo Heras2, Raquel Arranz Jiménez3
1Endocrine and Breast Surgery Unit, Department of General and Digestive Surgery, Instituto de Investigación, Hospital Universitario La Paz (IdiPAZ), Madrid, Spain. jgomezramirez@hotmail.com.
Thyroid gland size is not a significant risk factor for postoperative complications after thyroidectomy. This study found no increased risk of hypoparathyroidism or recurrent laryngeal nerve injury with larger thyroid glands.
Area of Science:
- Endocrine Surgery
- Surgical Oncology
- Head and Neck Surgery
Background:
- Thyroidectomy is a common surgical procedure with a low mortality rate.
- Postoperative complications such as hypoparathyroidism and recurrent laryngeal nerve injury can occur.
- Traditionally, thyroid gland size has been considered a risk factor, but its independent role is unclear.
Purpose of the Study:
- To investigate whether thyroid gland size is an independent risk factor for postoperative complications following total thyroidectomy.
Main Methods:
- Prospective study of 121 patients undergoing total thyroidectomy.
- Preoperative ultrasound calculated thyroid volume.
- Correlation of thyroid volume and specimen weight with postoperative complication incidence.
Main Results:
- No significant differences in transient or permanent hypoparathyroidism incidence across thyroid size quartiles.
- No increased risk of recurrent laryngeal nerve paralysis observed with larger glands.
- No correlation found between thyroid size and parathyroid gland visualization or accidental removal.
Conclusions:
- Thyroid gland size is not an independent risk factor for postoperative complications after thyroidectomy.
- Findings challenge the traditional assumption linking larger thyroid size to increased surgical risk.
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