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Updated: Jul 28, 2025

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating

Measurement of X-ray Beam Coherence along Multiple Directions Using 2-D Checkerboard Phase Grating

Published on: October 11, 2016

A laboratory-based beam tracking x-ray imaging method achieving two-dimensional phase sensitivity and isotropic

G Lioliou¹, C Navarrete-León², A Astolfo²

¹Department of Medical Physics and Biomedical Engineering, University College London, Malet Place, London, WC1E 6BT, UK. g.lioliou@ucl.ac.uk.

Scientific Reports

|May 29, 2023

Summary

This study introduces a novel mask design for beam tracking X-ray Phase Contrast Imaging. It enables high-resolution 2D imaging with single-direction scanning, significantly reducing scan times.

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Last Updated: Jul 28, 2025

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Published on: October 11, 2016

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Area of Science:

Medical Imaging
Physics
Materials Science

Background:

X-ray Phase Contrast Imaging (XPCi) offers enhanced sensitivity for material and biological imaging.
Current beam tracking XPCi methods, like Shack-Hartmann, require multi-directional scanning for 2D resolution, increasing acquisition time.
Achieving high spatial resolution is limited by mask aperture size and dithering precision.

Purpose of the Study:

To develop an improved mask design for beam tracking XPCi.
To enable two-dimensional phase sensitivity and isotropic resolution with reduced scanning requirements.
To demonstrate the efficacy of the new mask design in imaging phantoms and biological samples.

Main Methods:

A novel mask design using offset rows of circular apertures was developed.
This design facilitates two-dimensional phase sensitivity and isotropic resolution.
The method was tested using custom-built phantoms and biological specimens.

Main Results:

The new mask design allows for single-direction sample or mask stepping.
Quantitative phase retrieval was successfully achieved.
Near aperture-limited spatial resolutions were obtained in two orthogonal directions.

Conclusions:

The proposed mask design significantly optimizes beam tracking XPCi by reducing scan time.
It achieves high-resolution 2D phase imaging with isotropic resolution.
This advancement holds potential for improved diagnostic capabilities in medical and materials science applications.