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Updated: Jul 28, 2025

Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
Published on: March 12, 2015
Recent Advancement in H8-BINOL Catalyzed Asymmetric Methodologies
1School of Chemical Sciences, UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai, Kalina, Santacruz (E), Mumbai, Maharashtra 400098,India.
Abstract:
H8-BINOL, a partially reduced form of BINOL, is widely employed in a broad array of organocatalyzed asymmetric methodologies. Over the last 25 years, asymmetric organocatalysis has witnessed an incredible improvement, and an advancement still continues to get a single enantio-enriched product. The broad-spectrum applications of H8-BINOL organocatalyst in C-C bond formation, C-heteroatom bond construction, name reactions, pericyclic reactions, and one pot and multicomponent reaction are attracting the attention of researchers. A diversified unique H8-BINOL-based catalyst has been synthesized and screened for catalytic activity. In this Review we frame out the H8-BINOL catalyzed novel discoveries from the last two decades.
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