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Narcolepsy following COVID-19: A case report and review of potential mechanisms
Yazdani Roya1, Barzkar Farzaneh2, Almasi-Dooghaee Mostafa1
1Firoozgar Hospital, Department of Neurology, School of Medicine Iran University of Medical Sciences Tehran Iran.
Key Clinical Message:
The immune activation in COVID-19 may trigger narcolepsy in vulnerable patients. We suggest clinicians carefully evaluate patients with post-COVID fatigue and hypersomnia for primary sleep disorders, specifically narcolepsy.
Abstract:
The patient is a 33-year-old Iranian woman without a significant past medical history with the full range of narcolepsy symptoms that started within 2 weeks after her recovery from COVID-19. Sleep studies revealed increased sleep latency and three sleep-onset rapid eye movement events, compatible with a narcolepsy-cataplexy diagnosis.
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