Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

6.1K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.1K
The Retina01:32

The Retina

69.2K
The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.
69.2K
Unrenewable Cells00:50

Unrenewable Cells

2.3K
In humans, the photoreceptor cells of the eye and sensory hair cells of the ear lack stem cells. These cells are thus unrenewable and cannot be replaced when they are damaged or destroyed.
Photoreceptors
The retina is composed of several layers and contains specialized cells called photoreceptors. The photoreceptors (rods and cones) change their membrane potential when stimulated by light energy. There are two types of photoreceptors—rods and cones—which differ in the shape of...
2.3K
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

7.2K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
7.2K
Channel Rhodopsins01:11

Channel Rhodopsins

2.6K
Most organisms use photoreceptors to sense and respond to light. Examples of photoreceptors include bacteriorhodopsins and bacteriophytochromes in some bacteria, phytochromes in plants, and rhodopsins in the photoreceptor cells of the vertebral retina. The light-sensitive property of these receptors is because of the bound chromophores, such as bilin in the phytochromes and retinal in the rhodopsins.
Rhodopsins belong to the family of cell surface proteins called G-protein coupled receptors,...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dropless after cataract surgery (DACS): concepts, evidence and clinical potential.

Eye (London, England)·2026
Same author

Single-cell and spatial transcriptomic analyses of gene therapy-associated retinal inflammation in non-human primates.

Molecular therapy. Advances·2026
Same author

Functional methods for evaluating the efficacy of retinal optogenetic therapy for vision restoration.

Frontiers in neuroscience·2026
Same author

Evaluation of Routine Clinical Deployment of an Autonomous Artificial Intelligence Assistant for Cataract Follow-Up in the National Health Service.

Clinical ophthalmology (Auckland, N.Z.)·2026
Same author

Retinal Phenotype in Mucopolysaccharidosis Type III.

American journal of ophthalmology·2026
Same author

Geographic atrophy in age-related macular degeneration: phenotypic characterisation for clinical trial consideration.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same journal

Persistent placoid maculopathy: long term outcomes and prognostic factors.

Retina (Philadelphia, Pa.)·2026
Same journal

ANTI-VEGF THERAPY SWITCHING RETINAL DISEASES: Characterizing Clinical Manifestations and Common Involved Genes: ERRATUM.

Retina (Philadelphia, Pa.)·2026
Same journal

THE EFFICACY AND SAFETY OF SUBRETINAL BALANCED SALT SOLUTION INJECTION IN DIABETIC MACULAR EDEMA WITH HARD EXUDATES: ERRATUM.

Retina (Philadelphia, Pa.)·2026
Same journal

EVALUATING CLINICAL OUTCOMES OF AMNIOTIC MEMBRANE COVERAGE COMBINED WITH EARLY VITRECTOMY IN THE MANAGEMENT OF PERFORATING GLOBE INJURIES.

Retina (Philadelphia, Pa.)·2026
Same journal

Mid-Phase Hyperfluorescent Plaques as a biomarker of disease activity in Central Serous Chorioretinopathy: Clinical Course and Treatment Response - MICRoN report number Ten.

Retina (Philadelphia, Pa.)·2026
Same journal

Severe retinal non-perfusion is associated with fewer retinal lesions on ultra-wide field fundus photography in proliferative diabetic retinopathy.

Retina (Philadelphia, Pa.)·2026
See all related articles

Related Experiment Video

Updated: Jul 28, 2025

Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy
04:02

Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy

Published on: November 29, 2024

1.2K

PHOTORECEPTOR DAMAGE IN TERSON SYNDROME.

Tomasz Szeligowski1, Dun J Fu1, Noa Fernandez-Ledo1

  • 1Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.

Retina (Philadelphia, Pa.)
|May 30, 2023
PubMed
Summary
This summary is machine-generated.

Photoreceptor damage in Terson syndrome, characterized by outer retinal changes, leads to poor visual outcomes. This damage, potentially from intracranial pressure, shows incomplete recovery despite treatment.

More Related Videos

Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina
09:05

Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina

Published on: May 6, 2015

10.8K
Vibratome Sectioning Mouse Retina to Prepare Photoreceptor Cultures
11:22

Vibratome Sectioning Mouse Retina to Prepare Photoreceptor Cultures

Published on: December 22, 2014

17.9K

Related Experiment Videos

Last Updated: Jul 28, 2025

Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy
04:02

Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy

Published on: November 29, 2024

1.2K
Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina
09:05

Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina

Published on: May 6, 2015

10.8K
Vibratome Sectioning Mouse Retina to Prepare Photoreceptor Cultures
11:22

Vibratome Sectioning Mouse Retina to Prepare Photoreceptor Cultures

Published on: December 22, 2014

17.9K

Area of Science:

  • Ophthalmology
  • Neurology

Background:

  • Terson syndrome is associated with subarachnoid hemorrhage.
  • Clinical outcomes in Terson syndrome can be variable.

Purpose of the Study:

  • To describe photoreceptor damage in Terson syndrome.
  • To investigate the cause of inconsistent clinical outcomes in Terson syndrome.

Main Methods:

  • Clinical evaluation of six patients with Terson syndrome.
  • Retinal imaging to assess photoreceptor damage.

Main Results:

  • Consistent outer retinal changes, indicating photoreceptor damage, were observed in 11 eyes.
  • Photoreceptor damage showed poor correlation with intraocular hemorrhage.
  • Retinal abnormalities demonstrated incomplete recovery over 3.5 to 8 years, with variable impact on visual function.

Conclusions:

  • Photoreceptor damage is a distinct manifestation of Terson syndrome.
  • Transient outer retinal ischemia secondary to increased intracranial pressure may cause this damage.