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[Ranitidine in primary peptic ulcer in childhood complicated by acute hemorrhage]
Insights
This study highlights the effectiveness of Ranitidine in treating pediatric hemorrhagic ulcers, showing complete recovery and no relapses with good patient compliance and no side effects.
Area of Science:
- Pediatric Gastroenterology
- Pharmacology
- Internal Medicine
Background:
- Hemorrhagic ulcers in children present unique clinical challenges.
- Effective pharmacological management is crucial for pediatric patients.
Observation:
- A pediatric patient with acute hemorrhagic ulcers was treated with intravenous Ranitidine.
- The treatment was continued orally for an extended period.
Findings:
- Intravenous Ranitidine (50 mg thrice daily for 3 days) effectively managed acute hemorrhagic complications.
- Oral Ranitidine (150 mg twice daily for 2 months, then 150 mg once daily for 8 months) resulted in no observed relapses.
- Endoscopic examination confirmed complete anatomical recovery of the ulcer.
Implications:
- Ranitidine demonstrates significant efficacy and safety in managing pediatric hemorrhagic ulcers.
- Long-term oral therapy with Ranitidine ensures sustained healing and prevents recurrence.
- The drug's good compliance and lack of side effects make it a favorable treatment option for children.
Abstract:
The authors shortly report on the frequency and the peculiar clinical picture in the paediatric age. The usefulness of the pharmacological control (Ranitidine i.v. 50 mg thrice for 3 days) of acute haemorrhagic compliances is discussed in reference to the patient. The same drug was continued per os for two month at a dosage of 150 mg twice daily followed by 150 once daily for 8 months; during this period no relapses were observed and an endoscopic control did show the anatomical recovery of the ulcer. The authors underline also the good compliance and the absence of side effects of the drug employed.