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Author Spotlight: Revolutionizing Research on Vaginal Microbiome Interactions Using a Vaginal Chip

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Microbiota and seminal quality: A systematic review.

Isadora de Almeida Gomes¹, Paula Bruno Monteiro², Gabriel Acácio de Moura³

¹Graduating in biomedicine at the Christus University Center - UNICHRISTUS, Fortaleza, CE, Brazil.

JBRA Assisted Reproduction

|May 31, 2023

Summary

The human microbiota impacts health. Infertility in men may link to gut bacteria imbalances, with lower Lactobacillus and higher Prevotella linked to poor seminal quality.

Keywords:

male infertility microbiota seminal quality

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Area of Science:

Microbiology
Reproductive Health
Human Microbiome

Background:

The human microbiota, comprising resident microorganisms, significantly influences host health and disease.
Microbiota dysbiosis is implicated in various pathological processes, including male infertility.
Understanding the gut-semen axis is crucial for reproductive health.

Approach:

A systematic review was conducted to investigate the correlation between the human microbiota and seminal quality in men.
Searched PubMed, Medline, and Cochrane Library databases for relevant studies published between 2012 and 2022.
Analyzed 7 selected English-language papers.

Key Points:

Men with normal semen parameters exhibited a higher prevalence of Lactobacillus.
Patients experiencing seminal alterations showed a higher prevalence of Prevotella.
Specific microbial shifts are associated with variations in semen quality.

Conclusions:

The human microbiota composition is demonstrably correlated with seminal quality.
A decrease in Lactobacillus and an increase in other bacterial species, such as Prevotella, are observed in infertile men.
Further research into microbiota modulation may offer novel therapeutic strategies for male infertility.