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Computational Vaccine Design for Common Allergens

Nandini Ghosh1, Gaurab Sircar2, Sudipto Saha3

  • 1Department of Microbiology, Vidyasagar University, Midnapore, West Bengal, India.

Methods in Molecular Biology (Clifton, N.J.)
|May 31, 2023
PubMed

In this chapter, the steps of designing candidate vaccine molecules for allergen-specific immunotherapy (AIT) using immunoinformatics are described. The most modern approach of AIT deals with carrier-bound B cell epitope and multi-epitope vaccine molecules. The strategy for designing these molecules and the bioinformatics tools and servers used for that are discussed in detail here.

Keywords:
Allergen-specific immunotherapyCarrier-bound B cell epitopeHypoallergenicMulti-epitopeNon-anaphylactic peptideVaccine

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