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Updated: Jul 28, 2025
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Spontaneous Vitiligo in a Captive Rhesus Monkey (Macaca Mulatta)
Bárbara Cs Meireles1, Beatriz Goldschmidt2, Cláudia A Lopes2
1Department of Primatology, Institute of Science and Technology in Biomodels (ICTB), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil;,
Comparative Medicine
|June 1, 2023
Summary
Vitiligo, a depigmentation disorder, was diagnosed in a rhesus macaque. This case highlights the disease
Area of Science:
- Veterinary Dermatology
- Primate Pathology
- Autoimmune Diseases
Background:
- Vitiligo is a condition causing progressive depigmentation in humans and animals due to melanocyte loss.
- Its exact cause is unknown, but autoimmunity, genetics, and environmental factors are suspected.
Observation:
- A 16-year-old female rhesus macaque presented with increasing depigmented patches on skin and fur.
- Lesions were primarily located on the head and back.
Findings:
- Histopathology confirmed vitiligo by revealing an absence of melanocytes in the epidermis and dermis.
- Clinical history and diagnostic tests supported the diagnosis.
Implications:
- This case report contributes to understanding vitiligo in non-human primates.
- It underscores the importance of recognizing autoimmune skin conditions in diverse animal populations.
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