Related Experiment Video

Updated: Jul 28, 2025

Author Spotlight: Point-of-Care Ultrasound for Gastric Content Assessment and Risk Stratification in Perioperative Care
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Author Spotlight: Point-of-Care Ultrasound for Gastric Content Assessment and Risk Stratification in Perioperative Care

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Is it enough to observe less than 2 cm sized gastric SET?

In Kyung Yoo1, Young Kwan Cho2, Seong Whan Kim2

  • 1Division of Gastroenterology, Department of Internal Medicine, Cha Bundang Medical Center, Cha University College of Medicine, Seongnam-si, South Korea.

Surgical Endoscopy
|June 1, 2023
PubMed
Abstract

Insights

Endoscopic resection is effective for small gastric subepithelial tumors (SETs) under 2 cm. This study found a notable percentage of GISTs among these small SETs, highlighting their potential for malignant transformation.

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Endoscopic Therapeutics

Background:

  • Increased detection of gastric subepithelial tumors (SETs) due to enhanced screening endoscopy.
  • Current guidelines recommend surveillance for SETs < 2 cm.
  • Advancements in therapeutic endoscopy enable resection of small SETs.

Purpose of the Study:

  • To analyze histopathological features of small gastric SETs.
  • To evaluate the effectiveness of endoscopic resection for small gastric SETs.
  • To assess the risk of malignancy in small gastric SETs.

Main Methods:

  • Retrospective analysis of 74 patients undergoing endoscopic resection of gastric SETs (≤ 2 cm).
  • Evaluation of histopathology and en bloc resection outcomes.
  • Analysis of procedure time and patient outcomes.

Main Results:

  • Mean SET size was 11.69 mm; mean procedure time was 81.26 min.
  • Histopathological diagnoses included leiomyomas (28), GISTs (26), ectopic pancreas (14), lipomas (4), and neuroendocrine tumors (2).
  • Two GIST cases showed high-risk histology; all resections were successful and uneventful.

Conclusions:

  • Endoscopic resection is a viable option for small gastric SETs (< 2 cm).
  • Small gastric SETs include a significant proportion of GISTs, which have malignant potential.
  • Early detection and resection of small SETs are crucial for managing potential GISTs.
Keywords:
Endoscopic resectionGastric subepithelial tumorGastrointestinal stromal tumor

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