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Related Concept Videos

Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
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Inflammatory Bowel Disease V: Surgical Management01:21

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Tissue Transplantation01:24

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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Related Experiment Video

Updated: Jul 28, 2025

Small Bowel Transplantation In Mice
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Small Bowel Transplantation In Mice

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Small bowel transplant - novel indications and recent progress.

Noemi Zorzetti1,2, Ignazio Roberto Marino3, Salvatore Sorrenti2

  • 1General Surgery, Ospedale Civile "A. Costa", Alto Reno Terme, Bologna, Italy.

Expert Review of Gastroenterology & Hepatology
|June 2, 2023
PubMed
Summary

Intestinal transplantation numbers remain stable, with a slight increase in adult cases over the last five years. Advances in management and surgical techniques are improving outcomes, though immunosuppression remains a challenge.

Keywords:
Intestinal transplantationenteral autonomyhome parenteral nutritionintestinal failurequality of lifeshort bowel syndrome

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Related Experiment Videos

Last Updated: Jul 28, 2025

Small Bowel Transplantation In Mice
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Small Bowel Transplantation In Mice

Published on: August 20, 2007

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Tissue Engineering of the Intestine in a Murine Model
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Area of Science:

  • Gastroenterology
  • Transplantation Medicine
  • Surgical Innovation

Background:

  • Intestinal failure management advances have impacted intestinal transplant rates.
  • Bowel transplant numbers have remained stable, with a modest rise in the past five years.

Purpose of the Study:

  • To review new indications and trends in pediatric and adult intestinal transplantation.
  • To analyze changes in intestine transplantation over the last five years.

Main Methods:

  • Literature review of PubMed manuscripts.
  • Analysis of trends in adult and pediatric intestine transplantation.

Main Results:

  • Increased adult intestine transplants correlate with improved 1-year graft survival.
  • Better abdominal wall closure techniques contribute to transplant success.
  • Over-immunosuppression remains a key challenge in intestinal transplantation.

Conclusions:

  • Intestinal transplantation is indicated for patients with clear criteria and failed rehabilitations.
  • Novel indications and progress in bowel transplantation offer a promising future.
  • Continued research into immunosuppression is crucial for advancing the field.