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Pediatric ambulatory pertussis epidemiology in France, recent updates

C Levy1, R Cohen1, S Béchet2

  • 1ACTIV, Association Clinique et Thérapeutique Infantile du Val-de-Marne, Créteil, France; Clinical Research Center (CRC), Centre Hospitalier Intercommunal de Créteil, Créteil, France; Université Paris Est, IMRB-GRC GEMINI, Créteil, France; AFPA, Association Française de Pédiatrie Ambulatoire, Orléans, France.

Infectious Diseases Now
|June 2, 2023
PubMed

Insights

Pertussis and parapertussis cases were analyzed post-vaccine strategy changes. Adults and adolescents were the primary sources of contamination, highlighting the importance of vaccination status in pertussis control.

Area of Science:

  • Pediatric Infectious Diseases
  • Vaccinology
  • Epidemiology

Background:

  • Vaccine strategies for pertussis and parapertussis have undergone significant changes, including mandatory vaccination in 2018.
  • Understanding transmission dynamics is crucial for effective public health interventions.

Purpose of the Study:

  • To analyze the vaccination status, age distribution, and sources of contamination for pertussis and parapertussis cases.
  • To evaluate the impact of evolving vaccination recommendations on disease surveillance.

Main Methods:

  • Outpatient surveillance data from 2014 to 2022 were collected.
  • Confirmed cases of pertussis and parapertussis were identified and enrolled by 35 pediatricians.

Main Results:

  • A total of 73 confirmed cases (65 pertussis, 8 parapertussis) were reported.
  • In children under 6 years, the 2+1 vaccination schedule had more cases (22) than the 3+1 schedule (7).
  • The primary sources of contamination were identified as adults and adolescents.

Conclusions:

  • Vaccination status and identifying contamination sources are critical for assessing the effectiveness of pertussis vaccination recommendations.
  • Continued surveillance is necessary to adapt strategies against pertussis and parapertussis.
Abstract

Keywords:
ChildrenPertussisVaccine coverageVaccine strategy

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