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Updated: Jul 28, 2025

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
Curated and harmonized gut microbiome 16S rRNA amplicon data from dietary fiber intervention studies in humans
Cynthia I Rodriguez1, Ali Keshavarzian2, Bruce R Hamaker3
1Dept. of Ecology and Evolutionary Biology, University of California, Irvine, USA. cirodri1@uci.edu.
Abstract:
Next generation amplicon sequencing has created a plethora of data from human microbiomes. The accessibility to this scientific data and its corresponding metadata is important for its reuse, to allow for new discoveries, verification of published results, and serving as path for reproducibility. Dietary fiber consumption has been associated with a variety of health benefits that are thought to be mediated by gut microbiota. To enable direct comparisons of the response of the gut microbiome to fiber, we obtained 16S rRNA sequencing data and its corresponding metadata from 11 fiber intervention studies for a total of 2,368 samples. We provide curated and pre-processed genetic data and common metadata for comparison across the different studies.
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