Preeclampsia up to date-What's going on?

Area of Science:

• Obstetrics and Gynecology
• Maternal-Fetal Medicine
• Cardiovascular Health in Pregnancy

Background:

• Preeclampsia is a major hypertensive disorder of pregnancy.
• It is linked to placental malperfusion and multi-organ damage.
• Preeclampsia contributes significantly to global maternal and perinatal mortality rates.

Purpose of the Study:

• To review the latest advancements in preeclampsia prediction and prevention.
• To discuss current management strategies and long-term health outcomes for mothers and children.
• To explore the emerging association between COVID-19 and preeclampsia.

Main Methods:

• Comprehensive literature review of recent studies on preeclampsia.
• Analysis of data on prediction biomarkers (e.g., cfDNA, sFlt-1, PlGF).
• Synthesis of information on management protocols and long-term follow-up studies.

Main Results:

• Preeclampsia poses significant risks for chronic diseases later in life for both mother and child.
• Early prediction and timely intervention are crucial for improving outcomes.
• Emerging research suggests a potential link between COVID-19 infection and preeclampsia development or severity.

Conclusions:

• Preeclampsia requires a multi-faceted approach encompassing prediction, prevention, and management.
• Understanding long-term sequelae is vital for comprehensive maternal and child healthcare.
• Further research is needed to elucidate the impact of COVID-19 on preeclampsia and vice versa.