Related Experiment Video
Updated: Jul 28, 2025

Author Spotlight: Exploring Microglial Interactions with Stress-Response Circuitry Using the Limited Bedding and Nesting Model
Published on: July 12, 2024
Conditions of Birth and Early Childhood Developmental Risk for Mental Disorders
Felicity Harris1, Kimberlie Dean1,2, Oliver J Watkeys1,3
1Discipline of Psychiatry and Mental Health, School of Clinical Medicine, University of New South Wales, Sydney, NSW, Australia.
Insights
Identifying early childhood risk factors at birth can help detect children needing timely intervention. This study links birth-known factors to developmental vulnerability classes, enabling early support for better long-term outcomes.
Area of Science:
- Developmental Psychology
- Public Health
- Child Psychiatry
Background:
- Early childhood developmental vulnerability is linked to later mental illness and adverse outcomes.
- Identifying at-risk children early allows for timely preventative interventions.
- Risk factors identifiable at birth could facilitate early detection and support.
Purpose of the Study:
- To examine associations between 14 birth-known factors and early childhood risk class membership.
- To determine if birth factors can reliably predict children who will benefit from early intervention.
- To inform preventative strategies within the first 2000 days of life.
Main Methods:
- Analysis of associations between 14 birth-known factors and risk class membership.
- Study conducted on a large cohort of 66,464 children.
- Examination of distinct patterns of association for specific risk factors and outcomes.
Main Results:
- Risk class membership was associated with maternal mental illness, parental criminal charges, and being male.
- Prenatal child protection notification showed a unique association with misconduct risk.
- Specific birth factors demonstrated distinct patterns of association with different risk classes.
Conclusions:
- Risk factors known at birth can aid in the very early detection of children requiring intervention.
- Early identification facilitates targeted support within the critical first 2000 days.
- Findings support the development of proactive, evidence-based early intervention programs.
Abstract:
Distinct classes of children in the general population are at increased odds of later mental illness and other adverse outcomes according to patterns of early childhood developmental vulnerability. If certain risk factors known at the time of birth are reliably associated with membership in early childhood risk classes, then preventative interventions could be initiated in the earliest years of life. Associations between 14 factors known at the time of birth and membership in early childhood risk classes were examined in 66,464 children. Risk class membership was associated with maternal mental illness, parental criminal charges and being male; distinct patterns of association were shown for some conditions, for example, prenatal child protection notification was uniquely associated with misconduct risk'. These findings suggest that risk factors known at the time of birth could assist in very early detection of children who may benefit from early intervention in the first 2000 days.
More Related Videos
Related Concept Videos
Psychological and Sociocultural Causes of Schizophrenia
Socioemotional Development during Infancy
Primary Temperament Types
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Conduct Disorder
Autism Spectrum Disorder
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Oppositional Defiant Disorder
Diagnostic Criteria and...

