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Updated: Aug 6, 2026

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Bacterial Detection & Identification Using Electrochemical Sensors
Published on: April 23, 2013
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Target-switched artificial biochemical circuit for a versatile and sensitive colorimetric detection platform
Xianzhu Meng1, Huiwen Gu1, Xiaoli Yin2
1College of Chemistry and Environmental Engineering, Yangtze University, Jingzhou, 434023, P. R. China. yingatswu@126.com.
Abstract:
The presence of the target causes the structural switch of a metastable hairpin template probe (MH) for triggering a self-primed artificial biochemical circuit to produce numerous DNAzyme replicates, which in turn results in substantial signal amplification for highly sensitive colorimetric determination of nucleic acids.

