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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
[Molecular diagnosis of hand eczema]
Kristin Technau-Hafsi1,2, Natalie Garzorz-Stark3,4,5, Kilian Eyerich6,3
1Klinik für Dermatologie und Venerologie, Medizinische Fakultät, Universität Freiburg, Freiburg, Deutschland. kristin.technau@uniklinik-freiburg.de.
Background:
Because hand eczema is a diagnostic challenge even for experienced dermatologists, a correct diagnosis is essential to ensure success of specific therapies.
Objectives:
Prerequisites for successful molecular diagnostics in general and in hand eczema in particular are discussed.
Materials And Methods:
Basic research and opinion statement on new developments in molecular diagnostics are considered with a special focus on hand eczema.
Results:
The first molecular classifier to distinguish psoriasis from (hand) eczema signature has been introduced as CE-marked in vitro diagnostics (CE-IVD); many more biomarkers associated with diagnostics, theranostics, or natural course of the disease are currently being investigated.
Conclusions:
Diagnosis of hand eczema will be supported by molecular diagnostics in the near future; we are at the beginning of the molecular era in dermatology.
