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Related Experiment Video

Updated: Jul 27, 2025

Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis

Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis

Published on: June 9, 2018

Tracheobronchial Amyloidosis: A Case Report.

Mai Al Khatalin¹, Abdallah Dalal², Kerime Hatun Ozgen³

¹Present Address: Al-Hussein Salt New Hospital, Internal medicine Department, Salt, Jordan.

Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India

|June 5, 2023

Summary

Tracheobronchial amyloidosis was incidentally discovered in an asymptomatic elderly male during aortic valve repair workup. Diagnosis was confirmed via histopathological examination of tracheobronchial abnormalities found on chest CT.

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Published on: August 30, 2019

Area of Science:

Pulmonology
Cardiology
Pathology

Background:

Tracheobronchial amyloidosis is a rare condition involving amyloid deposition in the airways.
It often presents with respiratory symptoms, but can be asymptomatic.
Incidental findings on imaging necessitate further investigation.

Purpose of the Study:

To report a case of incidentally diagnosed tracheobronchial amyloidosis.
To highlight the importance of recognizing airway abnormalities during unrelated investigations.

Main Methods:

A case study of an elderly male patient.
Chest CT scan for aortic valve repair workup.
Histopathological examination for diagnosis confirmation.

Main Results:

Incidental tracheobronchial abnormalities were detected on chest CT.
Histopathological examination confirmed tracheobronchial amyloidosis.
The patient was asymptomatic prior to the incidental finding.

Conclusions:

Tracheobronchial amyloidosis can be found incidentally in asymptomatic patients.
Chest CT may reveal unexpected airway pathology.
Histopathology remains crucial for definitive diagnosis.