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Updated: Jul 27, 2025

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Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies
Published on: August 11, 2023
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KTP 532 Laser Assisted Surgery for Oral Cavity Malignancy-A Retrospective Study
Dipak Ranjan Nayak1, R Balakrishnan2, Pooja Dalakoti3
1Former Professor and Head of Department, Dept of Otorhinolaryngology- Head and Neck Surgery, Kasturba Medical College, Manipal, India.
Summary
KTP 532 laser excision effectively treats early oral cancers without reconstruction, showing high survival rates and minimal recurrence. This laser surgery offers a precise alternative with better patient outcomes.
Area of Science:
- Oncology
- Surgical Oncology
- Laser Medicine
Background:
- Oral malignancy presents significant treatment challenges.
- Conventional surgical approaches may involve extensive reconstruction and morbidity.
- Minimally invasive techniques are sought to improve patient outcomes.
Purpose of the Study:
- To evaluate the efficacy of KTP 532 laser in surgically managing early and early-advanced oral cancers.
- To assess outcomes without the need for primary site surgical reconstruction.
- To determine the safety and effectiveness of laser-assisted tumor excision.
Main Methods:
- Retrospective analysis of 67 patients with T1, T2, and early T3 oral malignancy (2000-2013).
- Tumor excision performed using KTP 532 laser, with or without neck dissection or adjuvant radiotherapy.
- Wound healing by secondary intention without reconstruction.
Main Results:
- High rate of no loco-regional residual disease (61/67 cases) at last follow-up.
- Overall mean survival of 81 months, with 3-year disease-free survival at 91%.
- Laser excision demonstrated precision, reduced morbidity, shorter hospital stays, and better functional results.
Conclusions:
- KTP 532 laser excision is a viable alternative for early oral malignancy treatment.
- This technique offers advantages in precision, reduced morbidity, and improved functional outcomes.
- Laser-assisted surgery provides a less invasive option compared to conventional methods.

