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Updates in toxicities associated with immune checkpoint inhibitors

Nina B Curkovic1, Douglas B Johnson2

  • 1Department of Medicine, Vanderbilt University School of Medicine, Nashville, USA.

Expert Review of Clinical Immunology
|June 5, 2023
PubMed
Summary

Immune checkpoint inhibitors (ICIs) offer cancer treatment benefits but can cause immune-related adverse events (irAEs). Understanding ICI toxicity pathophysiology and management is crucial for effective cancer care.

Keywords:
Anti-CTLA4Anti-PD-1Anti-PDL1Immune CheckpointImmune-related adverse eventSteroid-refractoryToxicityTreatment

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