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Postoperative Spinal 18 F-FDG PET Pseudoprogression Mimicking Malignancy
Penghao Liu, Jing Huang1, Jie Lu
1Department of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.
Clinical Nuclear Medicine
|June 5, 2023
Summary
This study highlights how initial spinal imaging may misdiagnose gliosis as malignancy. Positron emission tomography (PET) scans can show pseudoprogression, requiring careful interpretation to avoid unnecessary treatments.
Area of Science:
- Neuroscience
- Radiology
- Oncology
Background:
- A 60-year-old woman experienced left upper limb weakness, prompting an initial spinal MRI.
- The initial MRI identified a C2-C3 heterogeneous mass, which showed no abnormal activity on 18F-FDG PET scans.
- Surgical resection revealed gliosis, not malignancy, but the patient's symptoms persisted and worsened.
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