[Histopathology of the arterial wall after animal experiment microsurgical operations]

Histologic findings on microvessels of laboratory animals are reviewed. Lesions of the microvascular wall may be caused by preparation, microvascular clips and anastomosis. The intensity of the closing pressure of microclips as well as the clipping time influence the extent of the damage. Thrombosis of microarteries was not seen, even after a clipping time of 2 hours. The vascular lesions were reparable. Four different techniques of anastomosis used experimentally and clinically were compared: end-to-end suture anastomosis (absorbable and non-absorbable sutures), telescopic 2-suture anastomosis, sutureless telescopic adhesive anastomosis (fibrinogen, IMMUNO AG Wien), and telescopic 2-suture adhesive anastomosis. The tissue restitution was better in suture anastomosis carried out with absorbable sutures than performed with non-absorbable suture material. The sutureless telescopic adhesive anastomosis is a very gentle method, but the anastomoses are not always stable enough. The advantages of the telescopic 2-suture adhesive anastomosis (absorbable sutures, fibrinogen adhesive) are relatively small lesions of the vascular wall, good restitution and sufficient stability. The patency rate (96%) corresponds to that of the end-to-end suture anastomoses (94%). The clinical application of the telescopic anastomosis is estimated critically, and evidently it is more suitable for microarteries than for microveins.