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Parallel interrogation of the chalcogenide-based micro-ring sensor array for photoacoustic tomography.

Jingshun Pan1,2,3, Qiang Li1, Yaoming Feng1

  • 1School of Electronics and Information Technology, Guangdong Provincial Key Laboratory of Optoelectronic Information Processing Chips and Systems, Sun Yat-sen University, Guangzhou, 510275, China.

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This study introduces a novel photoacoustic tomography (PAT) system using a chalcogenide-based micro-ring sensor array and digital optical frequency comb (DOFC) for parallel interrogation. This advancement enables high-resolution imaging of dynamic biological samples with enhanced efficiency.

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Area of Science:

  • Biomedical Optics
  • Acoustic Imaging
  • Sensor Technology

Background:

  • Photoacoustic tomography (PAT) offers optical contrast with acoustic resolution, crucial for advanced biomedical imaging.
  • Progress in PAT relies heavily on sophisticated ultrasound sensor arrays.
  • On-chip optical ultrasound sensors show promise but are underexplored in PAT systems.

Purpose of the Study:

  • To demonstrate photoacoustic tomography (PAT) using a novel chalcogenide-based micro-ring sensor array.
  • To develop and validate a parallel interrogation method for the sensor array using a digital optical frequency comb (DOFC).
  • To showcase the system's capability in imaging dynamic and biological subjects.

Main Methods:

  • Fabrication and characterization of a 15-element chalcogenide-based micro-ring sensor array with high sensitivity and broad bandwidth.
  • Synthesis of a digital optical frequency comb (DOFC) for parallel optical interrogation of the sensor array.
  • Implementation of PAT using the developed sensor array and DOFC for imaging proof-of-concept samples.

Main Results:

  • The sensor array demonstrated a bandwidth of 175 MHz and a noise-equivalent pressure of 2.2 mPaHz-1/2.
  • Successful parallel interrogation with a single light source and photoreceiver was achieved.
  • High-quality PAT images were obtained for fast-moving objects, leaf veins, and live zebrafish.

Conclusions:

  • The chalcogenide-based micro-ring sensor array offers superior performance for PAT applications.
  • DOFC-enabled parallel interrogation provides an effective and efficient method for PAT systems.
  • This integrated approach significantly advances the potential of PAT for diverse imaging applications.