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Utility of line-field confocal optical coherence tomography in the pediatric population
Simone Cappilli1,2, Cristina Guerriero3,4, Azzurra Iacoangeli3,4
1Dermatologia, Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Rome, Italy - simo.cappilli@gmail.com.
Insights
Line-field confocal optical coherence tomography (LC-OCT) enhances diagnostic confidence for pediatric skin conditions. This non-invasive imaging technique aids in identifying common dermatological issues, leading to better treatment strategies.
Area of Science:
- Dermatology
- Medical Imaging
- Pediatrics
Background:
- Dermatological diagnosis has advanced with imaging technologies, but pediatric cases require special considerations.
- Non-invasive methods are preferred in children to minimize psychological distress and scarring.
- Line-field confocal optical coherence tomography (LC-OCT) is a high-resolution, non-invasive imaging technique for skin condition diagnosis.
Purpose of the Study:
- To analyze common indications for LC-OCT in pediatric patients.
- To evaluate the potential role of LC-OCT in clinical settings for children.
- To assess the impact of LC-OCT on diagnostic confidence in pediatric dermatology.
Main Methods:
- Retrospective review of medical charts for patients ≤18 years with equivocal skin lesions.
- Clinical, dermoscopy, and LC-OCT data were analyzed.
- Diagnostic confidence was assessed using a three-point scale before and after LC-OCT.
Main Results:
- 74 skin lesions in 73 pediatric patients were investigated using LC-OCT.
- Diagnostic confidence increased by 21.6% after incorporating LC-OCT findings.
- LC-OCT helped reduce diagnostic uncertainty, improving confidence scores.
Conclusions:
- LC-OCT provides valuable insights for identifying common pediatric skin conditions.
- The technique improves diagnostic confidence, enabling more tailored treatment approaches.
- LC-OCT is a promising tool for non-invasive pediatric dermatology evaluations.
Background:
In the last decades diagnosis of dermatological diseases has achieved a significant progress with the aid of imaging technologies. In pediatric population dermatologic procedural investigations require special considerations, skill sets, and knowledge. Avoiding unnecessary invasive procedures in children is highly recommended to reduce psychological disturbance and cosmetical scars. Line-field confocal optical coherence tomography (LC-OCT) is an innovative, high-resolution, non-invasive imaging technique, that is proving to be valuable in the diagnosis of different skin conditions. In this study, we aimed to analyze the most common indications for LC-OCT in pediatric age group, discussing its potential role in clinical setting.
Methods:
A retrospective review of the medical charts of patients ≤18 years of age, who were performed clinical, dermoscopy and LC-OCT for equivocal skin lesions, was conducted. Diagnostic confidence level was calculated for clinical/dermoscopic diagnosis alone and for combined clinical/dermoscopy and LC-OCT findings, based on a three-point scale ranging from 0% to 100%.
Results:
Seventy-four skin lesions in 73 patients [(39 (53.4%) females and 34 (46.6%) males, mean age 13.2 (range 5-18 years) years] were investigated with LC-OCT. Diagnosis was established with histopathology in 23/74 (31.1%) cases, while 51/74 (68.9%) skin lesions were monitored over time or treated with topical/physical therapy. High diagnostic confidence increased by 21.6% after LC-OCT assessment, meanwhile reducing low and average score.
Conclusions:
LC-OCT may add practical clues for the identification of common skin conditions in pediatric population, improving diagnostic confidence and consequent tailored approach.
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