LC-OCT Features of Confluent and Reticulated Papillomatosis of Gougerot-Carteaud Syndrome

Confluent and reticulated papillomatosis (CRP) is a rare acquired keratinization disorder. We report a 29-year-old woman with a 3-year history of mildly pruritic hyperpigmented papules on the back, flanks, abdomen, and groin, coalescing centrally into plaques with a peripheral reticulated pattern. Dermoscopy showed a cerebriform sulci-and-gyri-like network. LC-OCT revealed a markedly thickened hyperreflective stratum corneum, increased epidermal thickness, and a strongly undulated dermal-epidermal junction; a hyperreflective basal band may also be appreciable if consistently visible on the image set. Histopathology showed orthokeratotic hyperkeratosis, focal acanthosis, papillomatosis, and increased basal pigmentation, confirming the diagnosis of CRP. In this case, LC-OCT identified in vivo optical features corresponding to key histopathologic criteria of CRP and may support noninvasive clinicopathologic correlation.