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Updated: Jul 27, 2025

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice
Published on: November 27, 2019
INFLUENCE DU JEÛNE AU NIVEAU ORGANIQUE CHEZ PHILOSAMIA CYNTHIA WALKERI. POIDS ET INCORPORATION A LONG TERME D'ACIDES
1Biologic du Développement des Insectes, Département de Biologic générate et appliquée (L.A. C.N.R.S. n°243), 43, Boulevard du 11 Novembre 1918, 69621 Villeurbanne, France.
Abstract:
The weight of organs and course of long term incorporation of amino acids into proteins are followed during a 48 hr starvation in Philosamia cynthia walkeri. In each organ, both parameters follow synchroneous evolutions: decrease of weight and amount of radio-active proteins since the beginning of starvation in the fat body; rapid increase during the first 6-12 hr in the intestine and integument, then a decrease. In hemolymph, the amount of radio-active proteins increases during 6hr and is stable thereafter. In the same time, the acid-soluble radio-activity is more depressed in the fat body than in hemolymph, and less in the integument and silkgland than in hemolymph. These results are discussed in relation with the influence of the fat body on growth and metabolism regulations during starvation. Two main hypothesis are suggested: intense exportation of amino acids from fat body to hemolymph in order to maintain a high level of material in the internal milieu; continuation of the growth of organs during the first hrs of starvation partly supported by the fat body.
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