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Related Experiment Video

Updated: Jul 27, 2025

Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging

Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging

Published on: May 7, 2017

Editorial Special Section on Biomedical Diffuse Optics for the Brain.

Sergio Fantini¹

¹Department of Biomedical EngineeringTufts University Medford MA 02155 USA.

IEEE Open Journal of Engineering in Medicine and Biology

|June 8, 2023

Summary

This summary is machine-generated.

Diffuse optics, including functional near-infrared spectroscopy (fNIRS), noninvasively measure brain hemodynamics and oxygenation. This technology has evolved significantly since the 1970s for brain imaging applications.

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Last Updated: Jul 27, 2025

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Area of Science:

Neuroscience
Biomedical Optics
Medical Imaging

Background:

Diffuse optics utilizes near-infrared light to noninvasively assess cerebral hemodynamics and oxygenation through the scalp and skull.
The concept originated in the 1970s, leading to commercial cerebral oximeters in the 1990s.
Functional near-infrared spectroscopy (fNIRS) emerged in 1993 for functional brain activation studies.

Discussion:

fNIRS technology has advanced significantly since its inception.
Research has explored oscillatory cerebral hemodynamics for functional and diagnostic purposes.
Numerous reviews and special issues highlight the progress in noninvasive optical brain measurement.

Key Insights:

Near-infrared spectroscopy provides a noninvasive window into brain function.
fNIRS enables the study of brain activation and hemodynamics.
The field has a rich history and continues to evolve.

Outlook:

Continued development in diffuse optics for enhanced brain monitoring.
Expanding applications of fNIRS in clinical and research settings.
Further exploration of cerebral hemodynamics and oxygenation measurements.