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Qing Xia1, Dongyu Li2, Tingting Yu1

  • 1Huazhong University of Science and Technology, Britton Chance Center for Biomedical Photonics - MoE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics - Advanced Biomedical Imaging Facility, Wuhan, China.

Journal of Biomedical Optics
|June 8, 2023
PubMed
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In vivo skin optical clearing techniques improve light penetration for better imaging of skin structures and diseases. This rapidly developing field enhances diagnostic and therapeutic applications using optical methods.

Area of Science:

  • Biomedical Optics
  • Dermatology
  • Medical Imaging

Background:

  • Skin diseases are prevalent, and cutaneous microcirculation is linked to various conditions.
  • Optical imaging techniques offer non-invasive methods for skin analysis but are limited by scattering.
  • In vivo skin optical clearing is crucial for enhancing light penetration and imaging depth.

Purpose of the Study:

  • To review recent advancements in in vivo skin optical clearing methods.
  • To explain how optical clearing improves skin imaging performance.
  • To highlight applications in disease study and light-based therapy.

Main Methods:

  • Comprehensive literature review of the past decade.
  • Analysis of mechanisms, methods, and applications of in vivo skin optical clearing.
Keywords:
in vivo skin optical clearinglaser treatmentoptical imagingskin lesion

Related Experiment Videos

  • Focus on fundamental and clinical research.

    • Main Results:

    • Efficient in vivo skin optical clearing methods have been identified.
    • Optical clearing enhances various optical imaging techniques for deeper, finer skin information.
    • Applications include disease study and safe, effective light-induced therapy.

    Conclusions:

    • In vivo skin optical clearing has rapidly advanced in the last decade.
    • It plays a significant role in skin-related research and clinical applications.
    • This technique is vital for improving optical imaging and therapeutic outcomes in dermatology.