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Bilateral Exudative Retinal Detachments and Panuveitis in a Patient with Multiple Myeloma
Nam V Nguyen1,2, Eleni K Konstantinou1, Noha Sherif1,3
1National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA.
Ocular Immunology and Inflammation
|June 8, 2023
Summary
This case report highlights rare but serious eye complications, including exudative retinal detachments and panuveitis, in a multiple myeloma patient. Prompt treatment led to symptomatic improvement.
Area of Science:
- Ophthalmology
- Hematology
Background:
- Multiple myeloma (MM) is a hematologic malignancy.
- Ocular manifestations of MM can be diverse and impact vision.
Observation:
- A 54-year-old male with systemic MM and diabetic retinopathy presented with bilateral blurred vision and scotomas.
- Examination revealed bilateral exudative retinal detachments (RD) and panuveitis, characterized by intraretinal hemorrhages and subretinal fluid.
Findings:
- The patient's ocular findings of panuveitis and exudative RD were diagnosed in the context of his MM.
- Optical coherence tomography confirmed subretinal and intraretinal fluid in both eyes.
Implications:
- Bilateral exudative RD and panuveitis are rare but sight-threatening complications associated with multiple myeloma.
- Early recognition and treatment, including plasmapheresis and corticosteroids, may improve visual outcomes in such cases.
