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Updated: Jul 27, 2025

Generation of Oligodendrocytes and Oligodendrocyte-Conditioned Medium for Co-Culture Experiments
Published on: February 9, 2020
Remyelination by preexisting oligodendrocytes: Glass half full or half empty?
1Weill Institute for Neuroscience, Department of Neurology, University of California, San Francisco, CA, USA.
Abstract:
The central dogma in remyelination states that the primary cellular source for myelin repair are the oligodendrocyte precursor cells. In this issue of Neuron, Mezydlo et al.1 highlight the potential of preexisting oligodendrocytes as an alternative, albeit minor, source for new myelin, with implications for demyelinating disorder research and therapies.
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