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Related Concept Videos

Gastric Emptying01:16

Gastric Emptying

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Gastric emptying occurs when the stomach gradually releases chyme into the duodenum. When the stomach is distended, it triggers the release of gastrin, a hormone that promotes gastric acid secretion to aid in digestion. Additionally, stomach distension contributes to peristaltic waves that propel gastric contents toward the pyloric region. The gastroenteric reflex, on the other hand, primarily stimulates peristalsis in the intestines, facilitating the movement of contents further along the...
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Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

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Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
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Gastric Motility01:16

Gastric Motility

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Gastric motility is the coordinated contraction and relaxation of stomach muscles that convert ingested food into chyme, a semi-liquid substance ready for further digestion in the intestines. The process begins with the vagus nerve inducing the relaxation of the smooth muscles in the fundus and body of the stomach, allowing these regions to expand and accommodate up to approximately 1.5 liters of food and liquid.
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
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Assessment of the Gastrointestinal System I: Subjective Data01:17

Assessment of the Gastrointestinal System I: Subjective Data

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Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
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The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
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Stomach pH Regulation01:21

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The human body carefully regulates the internal pH of different organs to maintain homeostasis. For example, while the blood plasma maintains a neutral pH of 7, the stomach lumen has an acidic pH of 1.5 - 3.5. The low pH of stomach lumen helps kill pathogens in the food and break down complex food molecules.
The acid-secreting gastric mucosal epithelial cells (parietal cells) lining the stomach lumen maintain the low pH in the lumen. Numerous ion transporters and channels on these parietal...
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Assessment of the Gastrointestinal System II: Health Perception Pattern01:29

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Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
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Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
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Related Experiment Video

Updated: Jul 27, 2025

Author Spotlight: Point-of-Care Ultrasound for Gastric Content Assessment and Risk Stratification in Perioperative Care
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Author Spotlight: Point-of-Care Ultrasound for Gastric Content Assessment and Risk Stratification in Perioperative Care

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Gastric Alimetry

William Jiaen Wang, Daphne Foong, Stefan Calder

    Medrxiv : the Preprint Server for Health Sciences
    |June 9, 2023
    PubMed
    Summary
    This summary is machine-generated.

    Gastric Alimetry (GA) offers superior patient phenotyping for gastroduodenal disorders compared to gastric emptying testing (GET). GA improves diagnostic accuracy and personalized management by correlating better with symptoms and psychometrics.

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    Fabrication and Implantation of Miniature Dual-element Strain Gages for Measuring In Vivo Gastrointestinal Contractions in Rodents.

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    Area of Science:

    • Gastroenterology and Hepatology
    • Medical Device Technology
    • Clinical Diagnostics

    Background:

    • Chronic gastroduodenal symptoms significantly impact quality of life and healthcare costs.
    • Gastric emptying testing (GET) has limitations in specificity and sensitivity for diagnosing neuromuscular disorders.
    • Gastric Alimetry (GA) is a novel device integrating non-invasive gastric electrophysiological mapping with symptom profiling.

    Approach:

    • Simultaneous GET and GA were performed on 75 patients with chronic gastroduodenal symptoms.
    • GA involved a 30-minute baseline, a radiolabeled meal, and a 4-hour postprandial recording.
    • Symptom profiling via the GA App used rule-based criteria to phenotype patients.

    Key Points:

    • GA detected motility abnormalities in 33.3% of patients, compared to 22.7% for GET, with a combined yield of 42.7%.
    • GA symptom phenotypes showed superior correlations with validated symptom and anxiety scales (GCSI, PAGI-SYM) than GET or Rome IV criteria.
    • Delayed gastric emptying was not a predictor of specific GA phenotypes.

    Conclusions:

    • GA enhances patient phenotyping in gastroduodenal disorders, irrespective of motility abnormalities.
    • GA demonstrates improved correlation with patient symptoms and psychometric assessments compared to GET.
    • These findings support GA's potential for improved diagnostic profiling and personalized management of gastroduodenal disorders.