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Published on: February 11, 2022
Diagnosis and surgical management of pericardial constriction after cardiac surgery
Alejandra Castro-Varela1, Hartzell V Schaff1, Jae K Oh2
1Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minn.
Insights
Constrictive pericarditis after cardiac surgery often presents with right heart failure. Urgent pericardiectomy following initial surgery is linked to worse long-term survival for these patients.
Area of Science:
- Cardiology
- Cardiac Surgery
- Thoracic Surgery
Background:
- Previous cardiac surgery is a growing cause of constrictive pericarditis.
- Data on the clinical presentation and outcomes of surgical treatment for this condition are limited.
Purpose of the Study:
- To analyze the clinical presentation and outcomes of pericardiectomy in patients with constrictive pericarditis following cardiac surgery.
Main Methods:
- A retrospective review of 263 patients who underwent pericardiectomy for postoperative constriction between January 1, 1993, and July 1, 2017.
- Outcomes assessed included early and late mortality, and clinical presentation features.
Main Results:
- Median age was 64 years; median interval to pericardiectomy was 2.7 years.
- Common prior surgeries included coronary artery bypass grafting (43%) and valve surgery (32%).
- Right heart failure symptoms (84%) were the most common presentation; 5.5% had early mortality, with 5- and 10-year survival rates of 61% and 44%, respectively. Older age, diabetes, and nonelective pericardiectomy within 2 years of initial surgery were associated with decreased survival.
Conclusions:
- Pericardial constriction post-cardiac surgery can manifest at any time interval.
- Right heart failure symptoms in patients with prior cardiac surgery warrant consideration for constrictive pericarditis.
- Urgent pericardiectomy after cardiac surgery is associated with poor long-term outcomes.
Objectives:
Previous cardiac surgery is an increasingly common etiology of constrictive pericarditis, but there is a paucity of data on clinical presentation and outcome of surgical treatment.
Methods:
We reviewed data of 263 patients who underwent pericardiectomy for postoperative constriction from January 1, 1993, through July 1, 2017. Outcomes of interest were early and late mortality, as well as features of clinical presentation.
Results:
Median patient age was 64 (56-72) years, and the median interval between previous operation and pericardiectomy was 2.7 years (range, 0-54 years). Previous operations included coronary artery bypass grafting in 114 (43%), valve surgery in 85 (32%), combined coronary artery bypass grafting and valve surgery in 33 (13%), and other procedures in 31 (12%). Common presentations were symptoms of right heart failure in 221 (84%) or dyspnea in 42 (16%). Moderate-to-severe tricuspid valve regurgitation was present in 108 (41%) patients. There were 14 (5.5%) deaths within 30 days postoperatively, and survival at 5 and 10 years postoperatively was 61% and 44%. On multivariate analysis, older age (P = .013), diabetes (P = .019), and nonelective pericardiectomy within 2 years of cardiac surgery (P < .001) were associated with decreased long-term survival.
Conclusions:
Pericardial constriction after cardiac surgery can present at any interval postoperatively. Symptoms and signs of right heart failure in patients with previous cardiac surgery should alert physicians to the possibility of pericardial constriction followed by a correct diagnosis. Pericardiectomy performed urgently following cardiac operation has poor long-term outcomes.
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